According to PEOPLE, the foursome partied at Primehouse, sitting all together, sharing food and drinks. They looked like they were having a great time, according to an insider, and there were plenty of laughs to go around.

Aniston and Theroux seems to have a lot of friends over at SNL, and this is their second time in just as many weeks hanging out with people from the show. They seem to like going out with other friends and just having a good time.

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“What is great about Jen is that she’s consistent, she brought that same energy and sparkle, and that love of life that she brings to everything. She was really at home and really comfortable not being in front of the camera, I really envy her for that,” actress Jeanne Tripplehorn, who stars in Aniston’s forthcoming short film “Five,” told FOX411′s Pop Tarts column the Variety Power of Women event. “She was very specific, and nurturing and gentle. All the qualities we love about her, she had as a director.”

What’s even better is that Aniston’s directorial effort is all for a good cause, and guaranteed to bring tears to your eyes.

“‘Five’ is five short films, all dealing with a different character faced with the diagnosis of breast cancer. They face it with strength and dignity and a lot of humor,” Tripplehorn continued. “We had five amazing women who came together, Jen directed as well as Demi Moore, Alicia Keys, Penelope Spheeris and Patty Jenkins.”

Tripplehorn’s role as an oncologist serves as the common thread which weaves all the tales together, as she bears the burden of delivering the devastating news to her patients, which include the likes of Patricia Clarkson and Rosario Dawson.

“Five” will air on Lifetime during Breast Cancer Awareness Month in October. Check your local listings for times.

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The film, directed by five different women, features the gripping stories of five women dealing with breast cancer. Jeanne Tripplehorn (“Big Love”) playing the doctor is the only link among them.

Tripplehorn’s character, Pearl, has to tell the women they are sick. In the case of Clarkson’s character, Mia, about as sick as one can be since she’s diagnosed with Stage 4 cancer.

“It’s Stage 4 because I didn’t go get a mammogram,” Clarkson says. “She didn’t catch it early.”

“My piece was one of the most extraordinary things I ever read,” Clarkson says. “And it frightened me deeply. This piece ate my lunch. It was brutal.”

Mia has that raw honesty of those who run out of time. She drinks a bottle of Cristal a day, fritters away her savings and lives each day as if it were her last because it could be.

“I don’t look TV sick, I look sick sick,” Clarkson says.

It’s not spoiling anything to say that it ends well because this chapter of the movie is told from the end to the beginning.

Mia has massive rounds of chemotherapy, her longtime husband leaves her while she’s heaving from the chemo, and she even stages her own funeral. Given this subject matter, funny may not be the first word that jumps to mind.

“It’s funny, funny, funny,” Clarkson says. “With Jennifer Aniston directing the light and dark are ever present.”

“And then I live and marry Tony Shalhoub,” Clarkson says. “Who would not want to marry Tony Shalhoub?”

Clarkson recalls telling Aniston: ” ‘You are good as a director! Screw you! Go stand in the corner.’ Great actors make great directors.”

“When you see the whole piece, it is brutal,” Clarkson says. “All have been cut down to just the emotional life. Each is 20 minutes and in that span of time, you travel a distance.”

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